[Expanded Title] From My Perspective : ALL of «Existence» is a «Spiritual» (or ISBE) Phenomena
Therefore, for this reason, it is absolutely impossible not to have a spirit or be a «spirit» (or ISBE) in some form or capacity; how-ever, ISBEs can be corrupted, tainted, mind-controlled, manipulated, deceived™ (special-case due to literal inexperience & ignorance of not knowing the nature of what this even is at one's original creation-time), entrapped, convinced to adhere to an authoritarian mind-set, etc.; once they get to the point were ALL «sanity» and «reason» has left them, then, yes, they basically do become «as biological-robots» at that point, and, are then often described as sheeple, brain-washed (because they are), cult-members (because they are), NPCs (because they behave like one), normies (not sure how or why this ended up becoming a meme), etc. They are still «spirits» (or ISBEs), but, the «(false) programming» over their MINDS is SO strong, that, they become a danger unto both themselves and upon anybody else who is also still «contaminated» in some or any way.